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Fyxois MB-1 45+

Fyxois MB-1 45+

 

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What Makes MB-1 45+ Different From Every Other “Fix” You’ve Tried

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Boosts GLP-1 Levels Naturally

Clinically shown to raise GLP-1, the key hormone that calms cravings and balances hunger cues.

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Up to 18% Drop in Body Fat

By supporting GLP-1, estrogen, & cortisol, MB-1 45+’s ingredients address the root cause of menopause-related weight gain.

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Up to 97 More Calories Burned Per Day

Grains of Paradise boosts your resting metabolic rate through thermogenesis to help your body burn more calories at rest.

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Up to 16.4% Lower Serum Cortisol

KSM-66® reduces stress hormones to help with mood swings, sleep quality, and combat cortisol-related belly fat.

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Up to 12 Weeks to Reactivate Estrogen Through the Gut

Gyntima™ probiotic blend supports your body’s natural estrogen, which can help ease menopausal symptoms and discomfort.

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Up to 27.3% Reduction in LDL Cholesterol

IGOB131® helps reduce fatty acid production to support healthy triglycerides and LDL (bad cholesterol) maintenance.

  • Month 1

    Your Journey Begins

    • Cravings start to calm
    • Daily energy levels improve
    • Your body starts burning more calories at rest
  • Month 2

    Start to Feel the Change

    • Regulated leptin levels for balanced appetite*
    • Reduced cortisol to support mood, sleep & stress-related weight gain*
    • Healthy blood sugar & cholesterol maintenance*
  • Month 3+

    Start to See the Change

    • Up to 18% reduction in body fat
    • Boosted GLP-1 levels for balanced hunger cues
    • Supported estrogen levels for menopause-symptom relief

    After month 3, continue taking MB-1 45+ daily to maintain results and see further improvements in your metabolic and hormonal wellness. Remember that real results take time! Everybody is different, so results may vary depending on how long your system needs to adjust.

    • Vitamin B6 (P5P)

      The most bioactive form of B6—an essential vitamin that supports protein metabolism, reduces water retention, and regulates serotonin to promote emotional balance.

    • Chromium Picolinate

      An essential trace mineral that supports healthy blood sugar by enhancing insulin function and glucose uptake, helping to curb cravings and support metabolism.

    • African Mango (IGOB131®)

      A clinically studied extract that balances adiponectin and leptin to shrink fat cells, reduce LDL cholesterol, and regulate appetite.

    • Dichrostachys glomerata (DygloFit®)

      A clinically-studied African fruit extract that boosts GLP-1 to regulate appetite, improve satiety, and support healthy weight management.

    • Organic Ashwagandha (KSM-66®)

      A clinically studied adaptogen that lowers cortisol (the body’s main stress hormone) to support stress relief, emotional balance, and deeper sleep.

    • Grains of Paradise

      A clinically-studied West African spice that activates BAT (brown fat) to increase resting metabolic rate and daily calorie burn.

    • Green Tea Extract

      An herbal antioxidant that helps activate AMPK to support steady energy, healthy fat metabolism, and overall metabolic function.

    • Hormonal Support Probiotic Blend (Gyntima™)

      A clinically studied probiotic blend that supports estrogen reactivation through GUS enzyme activity in the gut to help ease menopausal symptoms and promote hormonal balance.

      Menopause May Be Inevitable, But “Just Pushing Through” Doesn’t Have To Be

      If you're a woman in perimenopause, menopause, or beyond - and you feel like a stranger in your body…

      If the clean eating, consistent workouts, and willpower that once worked now barely move the needle...

      You’re not broken, and you’re definitely not alone.

      MB-1 45+ was made for you. Our next-generation formula is designed to address the hormonal and metabolic shifts that begin around your mid-40s...

      Estrogen declines. Cortisol spikes up. Gut diversity changes. And your metabolism slows in ways that standard solutions don’t address.

      Built on the same foundation that made our original MB-1 formula a trusted favorite for over 1M+ women, MB-1 45+ has been rebuilt with clinically studied, precision-targeted ingredients—specifically for this next chapter of life.

      Because your body is evolving, and you deserves support that evolves with it.

      Frequently Asked Questions

      What’s the difference between MB-1 and MB-1 45+?

      MB-1 45+ builds on the powerful foundation of our original MB-1, but is carefully tailored to the unique changes women experience during perimenopause, menopause, and beyond. While it contains many of the same core ingredients to support metabolism, we’ve also added targeted ingredients to help address hormonal shifts, stress, and menopausal metabolic changes. With KSM-66® Organic Ashwagandha to ease stress and support restful sleep, DygloFit® for enhanced GLP-1 support, and a probiotic blend to support natural estrogen balance and ease common menopausal symptoms, MB-1 45+ was designed to offer a more advanced approach to menopausal wellness—helping you feel balanced, energized, and supported through every stage.

      How long does it take to start seeing results?

      MB-1 45+ was designed as a 3-month system that works with your body over time. Within the first month, you may notice more consistent energy and fewer cravings. By month two, metabolic rate and caloric burn will increase, along with improvements in sleep and stress levels and a more balanced appetite. By the third month of consistent use, you can expect to feel the formula's full effects including healthy weight management, improved hormonal balance, and an overall optimized metabolism. Pairing MB-1 45+ with a balanced diet and daily movement supports the most optimal results.

      Do I need to change my diet or exercise while taking MB-1 45+?

      MB-1 45+ was designed to work synergistically with a healthy lifestyle so pairing with balanced meals, movement, and adequate hydration will support even stronger results.

      Is MB-1 45+ safe for women in perimenopause or menopause?

      MB-1 45+ was designed for women in perimenopause and beyond. While the average age for women starting perimenopause is around 45 years old, this can vary significantly from woman to woman. Some women may begin noticing changes as early as their mid to late 30s, while others may not experience symptoms until their mid-50s. MB-1 45+ can provide support for metabolism, energy, and hormonal balance during this transition—no matter when perimenopause or menopause begins.

      Can I take MB-1 45+ if I’m on other medications or supplements?

      Though we are not aware of any interactions, if you have a medical condition or are currently taking a prescribed medication (including hormone replacement therapy (HRT), thyroid medication, weight loss medications, or GLP-1 drugs) we recommend consulting with your healthcare provider before starting any new supplements. MB-1 45+ is not intended to replace HRT or any other prescribed treatment, nor is it a treatment for medical conditions such as diabetes or obesity.

      That said, MB-1 45+ was formulated to work seamlessly with the rest of the Fyxois lineup. Depending on your goals, pairing it with other formulas can help enhance results:

      • Tone: Supports healthy muscle mass in postmenopausal women, key for metabolism and body composition.
      • Clear Protein+: Works synergistically by boosting protein intake, which helps increase metabolic rate and satiety.
      • Calm, Sleep, and Magnesium: Address stress and sleep—two of the biggest factors in metabolism—making MB-1 45+ even more effective.

      Together, MB-1 45+ and other Fyxois products offer a holistic approach to supporting metabolism, energy, and overall well-being.

      Why do I need to take MB-1 45+ for at least 3 months?

      MB-1 45+ is designed to work gradually with your body. We recommend taking it consistently for at least 3 months to experience the full benefits, as this allows enough time for your metabolism and hormones to respond and for sustainable changes to take place.

      After this point, you can continue taking MB-1 45+ for long-term maintenance and optimization of results. Pairing it with healthy habits—like daily movement and balanced meals—will further support lasting improvements in energy, metabolism, and overall well-being.

      Does MB-1 45+ contain any synthetic hormones?

      MB-1 45+ does not contain any synthetic hormones. It’s formulated with clinically studied plant extracts, probiotics, and nutrients that work with your body to support metabolism, energy, and hormonal balance for a more natural approach to menopausal wellness.

      What makes MB-1 45+ different from other weight loss or metabolism products?

      MB-1 45+ was specifically created to address the unique hormonal and metabolic shifts that occur during perimenopause, menopause, and beyond. Unlike generic weight management products, MB-1 45+ takes a 360° scientific approach, using clinically-backed ingredients to support multiple key mechanisms that influence fat loss and metabolism — including cortisol balance, appetite regulation, resting metabolic rate, and overall hormonal wellness. This comprehensive approach was designed to help you feel more energized, balanced, and supported through every stage.

      Will MB-1 45+ still work if nothing else has worked for me before?

      We created MB-1 45+ precisely for this reason. Many women entering perimenopause and beyond find that traditional weight management products and methods are either ineffective or stop working because they don’t address the deeper hormonal and metabolic changes that occur in these stages of life. MB-1 45+ was designed to be the most comprehensive, natural solution available, targeting these exact underlying shifts to help unlock real progress. With consistent use over 3 months, MB-1 45+ helps set the foundation for lasting metabolic results.

      Can I keep taking MB-1 45+ once I reach my goals?

      While we recommend taking MB-1 45+ for at least 3 months to see the full effects of the product kick in, many women choose to continue taking MB-1 45+ even after this point to help maintain or further optimize their results.

      Trustpilot reviews

      Excellent 4.8 / 5

      • Taste great, simple solution for taking creatine

        I have been taking Tone for a few months now and I’m very happy with the results. They taste good, not a bad texture and great results. I have noticed an improvement in my strength during my workouts and am noticing more muscle definition overall.

        Jasmine G

      • The best

        One of the only “bloat” products I’ve tried that actually makes a difference!! This helps me feel better after eating a large dinner. I akways have it on me, even when going out to dinner or traveling.

        Andrea S

      • I’m a convert!

        After 3 months with the product, I noticed that my body felt strong and toned and my appetite controlled. I have a strong desire to fuel myself with nutritious options and do not struggle with cravings at all!

        Lisa B